WEBVTT 00:00:01.555 --> 00:00:05.532 Generate: Biomedicines 00:00:05.760 --> 00:00:09.760 [GB-0895], [TSLP] GB-0895 is a type of medicine called a monoclonal 00:00:09.840 --> 00:00:14.320 antibody which has been designed to block a protein in the body called TSLP. 00:00:15.040 --> 00:00:19.360 TSLP can be released by cells in your body when they interact with items like 00:00:19.440 --> 00:00:21.760 allergens, irritants or infections. 00:00:23.800 --> 00:00:27.520 For patients with asthma, when there is too much TSLP that has been 00:00:27.600 --> 00:00:30.880 [Symptopms] released into your body, It triggers an inflammation response, 00:00:31.120 --> 00:00:34.400 which can make your airways swollen and narrow, which causes shortness 00:00:34.560 --> 00:00:36.720 of breath, coughing, and wheezing. 00:00:37.930 --> 00:00:38.711 GB-0895, Affinity, Half-life, Binding target 00:00:38.711 --> 00:00:42.080 GB0895 works by attaching itself to TSLP. 00:00:42.640 --> 00:00:47.680 When it attaches, TSLP is no longer able to trigger an inflammation response. 00:00:49.000 --> 00:00:52.800 GB0895 is also unique in being investigated 00:00:52.960 --> 00:00:58.000 further because it may be able to block TSLP more strongly directly in the lungs, 00:00:58.320 --> 00:01:02.880 and has also been shown in early studies to last last longer in the body before it breaks down. [Lasts longer in the body] 00:01:04.594 --> 00:01:05.968 The goal: fewer injections, easier treatment, fewer hospital visits 00:01:05.992 --> 00:01:07.840 This would mean fewer injections, which allows patients to keep up 00:01:07.920 --> 00:01:11.294 with treatment more easily, which hopefully would lead to fewer 00:01:11.360 --> 00:01:13.680 asthma flare-ups and hospital visits.